Tirzepatide 15 mg reconstituted with 4 mL

Concentration

3.75mg/mL

Per insulin unit
37.5 mcg
Solution in vial
400 u
2.5 mg draw
66.7 u

Math utility only — not medical advice. Not a recommended dose.

Units per dose at 3.75 mg/mL

Insulin syringes are graduated in hundredths of a millilitre, so units = mL × 100 on a U-100, U-50 or U-30 barrel alike.

DoseVolumeU-100 unitsFitsDoses per vial
2.5 mg0.667 mL66.7 uU-1006
5 mg1.333 mL133.3 usplit draw3
7.5 mg2 mL200 usplit draw2
10 mg2.667 mL266.7 usplit draw1
12.5 mg3.333 mL333.3 usplit draw1
15 mg4 mL400 usplit draw1

Amber rows exceed 100 units — more than one full U-100 barrel. That dose needs a larger draw or a stronger mix (less water).

How this is calculated

  1. 1 · Concentration

    15 mg ÷ 4 mL = 3.75 mg/mL

    The peptide mass never changes — bacteriostatic water only sets how concentrated the solution is, and therefore how far the plunger travels.

  2. 2 · Volume for a 2.5 mg dose

    2.5 mg ÷ 3.75 mg/mL = 0.667 mL

  3. 3 · Insulin units

    0.667 mL × 100 = 66.7 units

    Every unit on the barrel carries 37.5 mcg at this concentration, so misreading by one unit is a 37.5 mcg error.

See it on a real syringe

The interactive calculator draws this 3.75 mg/mL mix on a scaled U-100 barrel, shows when a draw lands exactly on a printed tick, and works backwards from a target dose to the water volume that makes it land cleanly.

Open the interactive calculator →

Common questions

How much bacteriostatic water for a 15 mg Tirzepatide vial?
Adding 4 mL of bacteriostatic water to a 15 mg Tirzepatide vial yields 3.75 mg/mL — 37.5 mcg in every insulin unit. The reconstituted vial holds 400 units of solution in total.
How many units is a 2.5 mg dose of Tirzepatide at 15 mg in 4 mL?
2.5 mg is 0.667 mL of this mix, which is 66.7 units on a U-100 insulin syringe (a U-100 barrel is enough).
How many 2.5 mg doses does a 15 mg vial give?
A 15 mg vial contains 6 full 2.5 mg doses. Using more or less bacteriostatic water changes the units you draw, never the number of doses in the vial.
All 211 reconstitution combinations →