Semaglutide 3 mg reconstituted with 4 mL

Concentration

0.75mg/mL

Per insulin unit
7.5 mcg
Solution in vial
400 u
500 mcg draw
66.7 u

Math utility only — not medical advice. Not a recommended dose.

Units per dose at 0.75 mg/mL

Insulin syringes are graduated in hundredths of a millilitre, so units = mL × 100 on a U-100, U-50 or U-30 barrel alike.

DoseVolumeU-100 unitsFitsDoses per vial
250 mcg0.333 mL33.3 uU-5012
500 mcg0.667 mL66.7 uU-1006
1 mg1.333 mL133.3 usplit draw3
1.7 mg2.267 mL226.7 usplit draw1
2.4 mg3.2 mL320 usplit draw1

Amber rows exceed 100 units — more than one full U-100 barrel. That dose needs a larger draw or a stronger mix (less water).

How this is calculated

  1. 1 · Concentration

    3 mg ÷ 4 mL = 0.75 mg/mL

    The peptide mass never changes — bacteriostatic water only sets how concentrated the solution is, and therefore how far the plunger travels.

  2. 2 · Volume for a 500 mcg dose

    0.5 mg ÷ 0.75 mg/mL = 0.667 mL

  3. 3 · Insulin units

    0.667 mL × 100 = 66.7 units

    Every unit on the barrel carries 7.5 mcg at this concentration, so misreading by one unit is a 7.5 mcg error.

See it on a real syringe

The interactive calculator draws this 0.75 mg/mL mix on a scaled U-100 barrel, shows when a draw lands exactly on a printed tick, and works backwards from a target dose to the water volume that makes it land cleanly.

Open the interactive calculator →

Common questions

How much bacteriostatic water for a 3 mg Semaglutide vial?
Adding 4 mL of bacteriostatic water to a 3 mg Semaglutide vial yields 0.75 mg/mL — 7.5 mcg in every insulin unit. The reconstituted vial holds 400 units of solution in total.
How many units is a 500 mcg dose of Semaglutide at 3 mg in 4 mL?
500 mcg is 0.667 mL of this mix, which is 66.7 units on a U-100 insulin syringe (a U-100 barrel is enough).
How many 500 mcg doses does a 3 mg vial give?
A 3 mg vial contains 6 full 500 mcg doses. Using more or less bacteriostatic water changes the units you draw, never the number of doses in the vial.
All 211 reconstitution combinations →